Lijecnicki vjesnik 2019;141(7-8)
Myelodysplastic syndromes – new discoveries and an “old” morphology
Gordana Kaić, Biljana Jelić Puškarić, Marina Pažur, Mia Šunjić Stakor, Slobodanka Ostojić Kolonić, Delfa Radić Krišto, Marko Martinović, Ika Kardum-Skelin
Abstract
Myelodysplastic syndromes (MDS) are a heterogenous group of diseases sharing some clinical and morphological features. Their cause is unknown. Since the rapid development of molecular genetics allows an insight into underlying genetic aberrations, today it is possible to determine some pathogenetic mechanisms in MDS. In this presentation we would like to explain some of the discoveries in this area and their connection to the myelodysplastic phenotype as seen in everyday cytomorphology work.