Lijecnicki vjesnik 2019;141(11-12)
Clinical Recommendation for Diagnostics, Treatment and Monitoring of Patients with Prostate Cancer
Mladen Solarić, Ana Fröbe, Dražen Huić, Dag Zahirović, Željko Kaštelan, Stela Bulimbašić, Igor Tomašković, Tomislav Kuliš, Marija Gamulin, Blanka Jakšić, Vesna Bišof, Ante Punda, Tomislav Omrčen, Tihana Boraska Jelavić, Katarina Vilović, Ana Marija Alduk, Kristijan Krpina, Tomislav Sorić, Zvonimir Curić, Borislav Belev
Abstract
Prostate adenocarcinoma is the most common solid neoplasm in male population in Croatia. It is often asymptomatic. The finding of PSA rise is the most common reason for diagnostic workout. Treatment plan is based on TNM classification, grade group and PSA. Clinically localized disease is successfully treated by radical prostatectomy or radiotherapy with or without hormonal therapy. Locally advanced disease is treated with radiotherapy and hormonal therapy. Metastatic disease can be controlled for many years by androgen deprivation. For castration resistant metastatic disease appropriate treatment is chemotherapy or secondary hormonal therapy. The following paper presents the clinical guidelines to standardize procedures for the diagnosis, treatment and follow-up of patients with prostate cancer in the Republic of Croatia.