Lijecnicki vjesnik 2015;137(3-4)
CLINICAL RECOMMENDATIONS FOR DIAGNOSIS, TREATMENT AND MONITORING OF PATIENTS WITH CANCER OF UNKNOWN PRIMARY SITE
Vesna Bišof, Antonio Juretić, Dragan Trivanović, Renata Dobrila Dintinjana, Božena Šarčević, JASMINKA JAKIĆ-RAZUMOVIĆ, Marija Ban, Lidija Bošković, Branka Petrić Miše, Miljenko Bura, Dinko Stančić-Rokotov
Abstract
Cancer of unknown primary (CUP) site comprises very heterogeneous group of various malignant tumors presented in metastatic phase of the disease. Diagnosis is set when primary site remains unidentified after a thorough diagnostic evaluation in patients with histologically proven malignant metastatic disease. Despite poor prognosis in most patients, favorable prognostic clinical entities have been recognized constituting the most important group of patients for oncological treatment. The following text presents the clinical guidelines in order to standardize the diagnosis, treatment and follow-up of patients with cancer of unknown primary site in the Republic of Croatia.