Lijecnicki vjesnik 2015;137(1-2)
A PATIENT WITH RHEUMATOID ARTHRITIS AND PRIMARY BILIARY CIRRHOSIS SUCCESSFULLY TREATED WITH ADALIMUMAB
Marija Bakula, Miroslav Mayer, Nada Čikeš, Branimir Anić
Abstract
Rheumatoid arthritis and primary biliary cirrhosis coexist in up to 6-% of cases. Tumor necrosis factor alpha seems to have an important role in the pathogenesis of both diseases. Tumor necrosis factor alpha inhibitors have become an established therapeutic regimen for patients with rheumatoid arthritis. The only approved drug for primary biliary cirrhosis is ursodeoxycholic acid. We describe the case of a female patient with both rheumatoid arthritis and primary biliary cirrhosis in a long term remission of both diseases induced with adalimumab. This case report is an important addendum to a few published similar reports.