Lijecnicki vjesnik 2010;132(9-10)
EFFECTS OF PNEUMOPERITONEUM ON LIVER FUNCTION
Višnja Nesek Adam, Žarko Rašić, VIVIANA MRŠIĆ, Elvira Grizelj Stojčić, ZORAN ČALA
Abstract
Summary. Effects of pneumoperitoneum on liver function during laparoscopic procedures in most patients have no clinical relevance. However, with increasing number and types of surgical procedures the laparoscopic operation is now performed in high-risk patients, including patients with pre-existing liver disease. In these patients laparoscopic procedures may lead to serious complication, including acute liver failure. Because postoperative liver damage induced by pneumoperitoneum has been underestimated, the aim of this article is to review the numerous factors influencing liver damage during laparoscopy and review of therapeutic options for their reduction.